April 2025
Our paper, Bridging Self-Supervision and Mechanism of Action Discovery in Morphological Profiling, in collaboration with the University of Surrey, has been accepted for the 1st CVPR Workshop on Computer Vision For Drug Discovery (CVDD) to be held in Nashville.
It introduces TRex — a task-guided framework that enhances the biological relevance of morphological embeddings for mechanism of action classification. TRex doubles performance, and improves compound recognition and generalisation — all without retraining large models.
This underscores the value of lightweight, task-aware adaptation for unlocking the full biological relevance of morphological profiling.
August 2024
ForecomAI’s work predicting which patients with venous thromboembolism may benefit from an extended anticoagulation 3 months post diagnosis, with collaborators from Pfizer and Bristol Myers Squibb among others, was presented at the European Society of Cardiology Congress in London.
A Cohen, S Choudhuri, I Khan, K Pollock, M Bober-Irizar, Z Galias, A Irizar, M Bober, A novel dynamic risk score to predict venous thromboembolism (VTE) recurrences after 3 months of anticoagulation in patients with incident VTE and without active cancer, European Heart Journal, Volume 45, Issue Supplement_1, October 2024, ehae666.2214, https://doi.org/10.1093/eurheartj/ehae666.2214
A Cohen, S Choudhuri, I Khan, K Pollock, M Bober-Irizar, Z Galias, A Irizar, M Bober, A novel dynamic risk score to predict Clinically Significant Bleeding (CSB) after 3 months of anticoagulation in patients with incident Venous ThromboEmbolism (VTE) and without active cancer, European Heart Journal, Volume 45, Issue Supplement_1, October 2024, ehae666.2215, https://doi.org/10.1093/eurheartj/ehae666.2215
May 2023
AI developed in the UK is the world leader in identifying the location and expression of proteins. Press release from University of Surrey.
May 2023
Our work on the development of the advanced AI system, HCPL (Hybrid subCellular Protein Localiser) for single-cell image analysis for protein localisation, is published in Communications Biology of the Nature Portfolio.
This technique can rapidly identify the subcellular localisation of proteins of interest in images, streamlining high throughput screening for various applications including the study of tumour heterogeneity, identification of disease and toxicity biomarkers, and drug discovery.
Husain, S.S., Ong, EJ., Minskiy, D. et al. Single-cell subcellular protein localisation using novel ensembles of diverse deep architectures. Commun Biol 6, 489 (2023). https://www.nature.com/articles/s42003-023-04840-z
May 2021
ForecomAI scientists won silver medal in a global competition to design single-cell AI analysis method that can automatically determine subcellular distribution of proteins from microscopy images. The competition was based on the Human Protein Atlas (https://www.proteinatlas.org/) and over 700 teams competed worldwide on the ML platform Kaggle.
Automated cell analysis methods are essential to support the ongoing revolution in biology, which promises to advance understanding of how human cells function, how diseases develop and how to cure them.
October 2020
ForecomAI has embarked in a collaboration with a pharmaceutical alliance to undertake machine learning methodology to develop and evaluate a novel risk prediction algorithm for the cardiovascular risk of pharmacological treatments using CPRD real world data.